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With PrusaSlicer, you can print multiple models at once, each with slightly different settings. For example, with different infill or layer height.

Right-click (Advanced mode) on a model and pick either:

Infill
Layers and perimeters
Support material

In the Expert mode, an additional Add settings option is available that lets you adjust settings such as speed, extrusion width, infill/perimeter overlap and more.

Alternatively, you can right-click on the editing icon in the Object list.

Original Prusa MMU3

Advanced features

Per model settings