Hi!
The MMU3 would definitely work together with the old MMU2S chimney too.
As an official solution, we suggest updating the chimney - as the MMU3 chimney is easier to calibrate.
If you wish to use the printer as a single material after insatalling the MMU3 onto it,
you can either turn off the MMU in the menu, or use the MMU Single profile and select a filament to use once you start the print.
Filament runout detection might be tricky though, as the chimney rather detects if the filament is inbetween the Bondtech gears - and if it runs out there, the wheels might no longer be able to catch and unload it. Then, you might need to remove the extruder-idler-mmu part and remove the filament leftover manually.